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KMID : 1134820120410101338
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Journal of the Korean Society of Food Science and Nutrition
2012 Volume.41 No. 10 p.1338 ~ p.1345
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Antioxidative and Physiological Activities of Fractions from Pleurospermum kamtschaticumin Extracts
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Kim Mi-Seon
Kim Kyoung-Hee
Yook Hong-Sun
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Abstract
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This study investigated the antioxidant activities, whitening effects, and antimicrobial activities of fractions from Pleurospermum kamtschaticumin extract. Total polyphenolic contents of fractions from Pleurospermum kamtschaticumin extract were 116.44～382.73 mg/g GAE (gallic acid equivalent), with the highest value in the ethyl acetate fraction. Fractions of Pleurospermum kamtschaticumin showed the highest DPPH (1,1-diphenyl-2- picrylhydrazyl) radical scavenging activity (IC50=0.04 mg/mL) and ABTS radical scavenging activity (98.86% at 0.5 mg/mL), which was similar to ascorbic acid. Further, reducing power and FRAP activity were significantly high in the ethyl acetate and n-butanol fractions. The ethyl acetate and n-butanol fractions showed significantly high SOD-like activities (1 mg/mL, 86.93%, and 78.23%, respectively) compared to other fractions. Tyrosinase inhibition activities of the n-butanol fraction and 80% ethanol extract were 43.52% and 41.64%, respectively. Antimicrobial activity against Escherichia coli was only observed in the chloroform fraction (16.7 mm in 0.5 mg/disc). These results suggest that fractions from Pleurospermum kamtschaticumin extract show comparatively high antioxidant activity and thus could be used as a food additive or cosmeceutical ingredient.
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KEYWORD
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Pleurospermum kamtschaticumin, antioxidant, free radical, tyrosinase, antimicrobial activity
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